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[Detection of anti-HCV antibodies in patients on long-term hemodialysis]

N Vasiljević, J Taseski

    Vojnosanitetski Pregled
    |February 24, 2001
    PubMed

    Insights

    Hepatitis C virus (HCV) infection is common in chronic dialysis patients, affecting nearly half of those studied. The number of blood transfusions received was linked to a higher risk of HCV infection.

    Area of Science:

    • Hepatology
    • Infectious Diseases
    • Nephrology

    Context:

    • Hepatitis C virus (HCV) infection poses a significant health challenge, particularly for individuals undergoing chronic dialysis.
    • Chronic dialysis patients are a vulnerable population for liver disease, with HCV being a leading cause.
    • Understanding the prevalence and risk factors of HCV in this demographic is crucial for patient care.

    Purpose:

    • To evaluate the prevalence of Hepatitis C virus (HCV) infection among patients undergoing chronic hemodialysis.
    • To investigate the association between HCV infection and the number of blood transfusions received by these patients.
    • To determine the clinical significance of HCV in a cohort of chronic dialysis patients at the Military Medical Academy.

    Summary:

    • A study involving 96 chronic hemodialysis patients assessed the presence of anti-HCV antibodies.
    • Results indicated a significant correlation between the detection of anti-HCV antibodies and the cumulative number of blood transfusions.
    • Approximately 48.95% of the studied hemodialysis patients were confirmed to have HCV infection.

    Impact:

    • Highlights the high prevalence of Hepatitis C in chronic dialysis patients, underscoring the need for screening and prevention strategies.
    • Identifies blood transfusion history as a key risk factor for HCV acquisition in this population.
    • Informs clinical practice regarding liver disease management and infection control in hemodialysis units.

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