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Related Experiment Videos

Continuous administration of contrast medium for transcranial colour-coded sonography.

U Schminke1, L Motsch, A Bleiss

  • 1Department of Neurology, Ernst Moritz Arndt University, Greifswald, Germany. schminke@neurologie.uni-greifswald.de

Neuroradiology
|February 24, 2001
PubMed
Summary

Continuous administration of contrast media in transcranial color-coded sonography (TCCS) provides sustained intracranial vessel enhancement. This method avoids blooming artifacts and extends the effective examination time, improving diagnostic quality.

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Area of Science:

  • Neurology
  • Radiology
  • Medical Imaging

Background:

  • Transcranial color-coded sonography (TCCS) is vital for intracranial vessel assessment.
  • Bolus injection of contrast media causes blooming artifacts and rapid enhancement decay.
  • Limited effective enhancement time hinders comprehensive TCCS examinations.

Purpose of the Study:

  • To evaluate continuous contrast medium administration in TCCS.
  • To assess the impact of a constant infusion rate on enhancement duration and quality.
  • To mitigate blooming artifacts associated with bolus injections.

Main Methods:

  • 28 TCCS examinations in 26 patients using a 2.25 MHz phased-array transducer.
  • Continuous infusion of 4g Levovist at 60 ml/h into an antecubital vein.

Related Experiment Videos

  • Subjective grading of contrast enhancement over time by two independent observers.

    • Main Results:

    • A stable contrast enhancement level was achieved after approximately 60 seconds.
    • Sustained enhancement lasted for over 660 seconds, confirmed by both observers.
    • Minimal inter-observer variability ( -10.1% to 9.9%) and no significant initial blooming artifacts were observed.

    Conclusions:

    • Continuous contrast medium infusion is a superior method for TCCS.
    • This technique significantly prolongs effective enhancement time for intracranial vessels.
    • It offers improved diagnostic imaging by reducing artifacts and maintaining consistent enhancement.