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Comparable implantation rates with fresh vs frozen embryo transfer suggests that controlled ovarian hyperstimulation
J H Check1, D Katsoff, D Brittingham
1The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, USA.
Purpose:
A retrospective comparison of fresh vs frozen embryo pregnancy rates.
Methods:
All frozen embryos transferred used in the analysis including deselected embryos from the oocyte retrieval cycle, and twice-frozen embryos.
Results:
Pregnancy and implantation rates following fresh or frozen embryo transfers were similar.
Conclusion:
The similar outcomes despite the obvious disadvantages for the frozen-thawed embryo suggests that some other factor reduces the chance of embryo implantation on oocyte-retrieval cycles. An adverse affect of controlled ovarian hyperstimulation on the uterine environment is a strong possibility.