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[A case of rhabdomyolysis after open heart surgery in a child]
N Suzuki1, M Yoshioka, N Shime
1Department of Anesthesiology, Shinkoga Hospital, Kurume 830-0037.
Insights
Rhabdomyolysis, a rare complication of cardiopulmonary bypass (CPB), can occur after pediatric heart surgery. Early diagnosis and forced diuresis are crucial for preventing acute kidney injury in these patients.
Area of Science:
- Cardiology
- Pediatric Surgery
- Nephrology
Background:
- Rhabdomyolysis is typically associated with trauma or conditions like malignant hyperthermia.
- Pediatric cardiac surgery, particularly procedures involving cardiopulmonary bypass (CPB), presents unique risks.
- Aortic regurgitation necessitates complex surgical interventions in children.
Observation:
- An 8-year-old girl developed rhabdomyolysis post-Ross-Konnos operation for aortic regurgitation.
- Ventricular fibrillation occurred after initial CPB weaning, necessitating re-initiation and rapid cooling.
- Prolonged CPB (5 hr 43 min) was followed by myoglobinuria, skin lesions, and markedly elevated CPK levels.
Findings:
- The patient exhibited signs of rhabdomyolysis, including elevated creatine phosphokinase (CPK) levels up to 19,132 IU/L.
- Intraoperative hypoperfusion during CPB was identified as the likely cause of rhabdomyolysis.
- Despite the severity, the patient recovered well with diuretics and aggressive fluid management, avoiding acute renal failure.
Implications:
- Rhabdomyolysis is a rare but significant complication following pediatric cardiopulmonary bypass.
- Prompt recognition and management, including forced diuresis, are vital for preventing renal complications.
- This case highlights the importance of vigilant monitoring for rhabdomyolysis in pediatric cardiac surgery patients.
Abstract:
Rabdomyolysis usually occurs after trauma and release of myoglobin from the damaged muscle, i.e.; after ishchemic myopathy due to arterial occlusion or malignant hyperthermia. We encountered a pediatric case of rhabdomyolysis after Ross-Konnos' operation in an 8-yr-old girl with aortic regurgitation. After the first weaning from cardiopulmonary bypass (CPB), ventricular fibrillation occurred due to an insufficiency in coronary blood flow and CPB was resumed with rapid cooling of body temperature. The total CPB lasted for 5 hr 43 min. After the second weaning from CPB, myoglobinuria was found. Furthermore, blisters and abrasions appeared on her back and CPK levels were abnormally elevated (maximum 19,132 IU.l-1) without any elevation of body temperature in the postoperative course. Rhabdomyolysis due to intraoperative hypoperfusion was suspected and diuretics were administrated with a large amount of crystalloid to maintain urine output. The patient showed a good clinical course without acute renal failure. The course of this case suggests that rhabdomyolysis is one of rare complications of CPB and an early correct diagnosis of rhabdomyolysis and forced diuresis at an early stage are important to avoid acute renal failure.
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