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[Blood purification in toxicology]
1Department of Nephrology, Jichi Medical School, Tochigi, Japan.
Although toxic substances can be removed by blood purification techniques such as hemodialysis and hemoperfusion, the complete elimination of toxic substances from the whole body is difficult even if clearance values are high. Blood purification over in a limited time sometimes cannot prevent the death of patients, because the volume of distribution of toxic substances is usually very high. It should also be stressed that initial general management of patients is very important whenever blood purification procedures are utilized.
Although toxic substances can be removed by blood purification techniques such as hemodialysis and hemoperfusion, the complete elimination of toxic substances from the whole body is difficult even if clearance values are high. Blood purification over in a limited time sometimes cannot prevent the death of patients, because the volume of distribution of toxic substances is usually very high. It should also be stressed that initial general management of patients is very important whenever blood purification procedures are utilized.