Related Experiment Videos
A girl with severe fistulizing Crohn's disease
A Barabino1, E Castellano, P Gandullia
1Paediatric Gastroenterology, G. Gaslini Institute for Children, Genoa, Italy. abarab@tin.it
Abstract:
We report the case of a girl with a severe perianal fistulizing Crohn's disease who during intravenous infusion of cyclosporine developed headache, general seizures and cortical blindness. Head magnetic resonance imaging showed spread, cortical-subcortical nonenhancing signal changes. Full neurological recovery was achieved in 24 hours. Cyclosporine was stopped and a single dose of infliximab was infused with rapid improvement of the fistula that at 7 months' follow-up is still closed.