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High-performance liquid chromatography chiral stationary phases based on low-molecular-mass selectors
F Gasparrini1, D Misiti, C Villani
1Dipartimento di Studi di Chimica e Tecnologia delle Sostanze Biologicamente Attive, Università La Sapienza, Rome, Italy. francesco.gasparrini@uniroma1.it
Journal of Chromatography. A
|February 24, 2001
Abstract:
A review of HPLC chiral stationary phases (CSPs) based on low molecular mass selectors is given. The review is focused on brush- and monomeric-type CSPs obtained by covalent linkage of chiral selectors, with emphasis on those obtained by total synthesis. Emphasis is given to new, emerging aspects like enantioseparations on receptor-like chiral stationary phases and dynamic enantioselective chromatography of stereolabile compounds.