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Cardiac thrombosis in a patient with Behçet's disease: two years follow-up
Y Basaran1, M Degertekin, H Direskeneli
1Kosuyolu Heart and Research Hospital, Istanbul, Turkey. mbasaran@sim.net.tr
Insights
A patient with Behçet
Area of Science:
- Cardiology
- Rheumatology
- Pathology
Background:
- Behçet's disease is a rare multisystem inflammatory disorder.
- Cardiac involvement, including thrombosis, can occur but is uncommon.
- This case highlights a significant cardiac manifestation in a young adult.
Observation:
- A 28-year-old male with known Behçet's disease presented with cardiac symptoms.
- The patient had a history of oral and genital ulcers.
- Echocardiography revealed cardiac thrombosis.
Findings:
- Despite anticoagulant and immunosuppressive therapy, the patient experienced recurrent thrombosis.
- Surgical excision of the thrombus was performed.
- Histological examination confirmed an organizing thrombus, indicating chronic inflammation.
Implications:
- This case underscores the potential for severe cardiac complications in Behçet's disease.
- It emphasizes the need for vigilant cardiac monitoring in affected individuals.
- Recurrent cardiac thrombosis may necessitate aggressive management strategies beyond standard medical therapy.
Abstract:
A 28-year-old man with Behçet's disease was presented with cardiac symptoms in addition to previous complaints of oral and genital ulcers. A diagnosis of thrombosis was made and patient began to receive anticoagulant and immunosuppressive therapy and was followed by echocardiographic examination. Despite medical therapy, thrombosis recurred. Surgical excision was performed and histological findings were consistent with organizing thrombus. Nature of cardiac involvement and review of literature on cardiac thrombosis in Behçet's disease was discussed.