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Brain SPECT in clinical practice. Part I: perfusion
1Nuclear Medicine Department, Autonomous University of Barcelona, Hospital de Sant Pau, Spain.
Summary
Brain perfusion SPECT (single-photon emission computed tomography) is a valuable neuroimaging tool for diagnosing and managing central nervous system diseases. This article guides clinicians on its effective use and interpretation for maximum patient benefit.
Area of Science:
- Neuroscience
- Radiology
- Medical Imaging
Background:
- Brain perfusion SPECT is a noninvasive functional neuroimaging technique.
- It studies physiological and pathophysiological events in the human brain.
- SPECT has demonstrated potential in patient management for various central nervous system diseases.
Purpose of the Study:
- To provide fundamental knowledge on performing brain perfusion SPECT in clinical practice.
- To offer an overview of the clinical value of SPECT in neuroscience research and patient care.
- To guide interpretation and reporting of brain perfusion SPECT images for maximum clinical benefit.
Main Methods:
- Overview of the clinical value of brain perfusion SPECT.
- Explanation of cerebral physiology relevant to SPECT imaging.
- Discussion of practical considerations including quantification and interventional studies.
Main Results:
- Brain perfusion SPECT is clinically valuable in diagnosis, therapeutic management, and follow-up of patients.
- The technique is a successful research tool in neurosciences due to the complexity of CNS diseases.
- Proper technique and interpretation are crucial for realizing the full potential of brain perfusion SPECT.
Conclusions:
- This article offers step-by-step recommendations for interpreting and reporting brain perfusion SPECT images.
- Understanding cerebral physiology is essential for proper interpretation of SPECT images.
- Brain perfusion SPECT, when used appropriately, provides significant clinical benefit in managing neurological conditions.