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Updated: Oct 9, 2026

Static Adhesion Assay for the Study of Integrin Activation in T Lymphocytes
Published on: June 13, 2014
Focal adhesion kinases: interest in immunoendocrinology, developmental biology, and cancer
1Department of Medicine, Institute of Pathology, University of Liege, Liege-Sart Tilman, Belgium. hmartens@ulg.ac.be
Abstract:
The research field on focal adhesion-related kinases started a decade ago, but the term focal adhesion was introduced for the first time nearly 20 yr before. Since its identification, many studies have enlightened the role of the first intermediate of focal adhesion-related signals in a large number of biologic and physiologic processes. In this review, we try to integrate the most recent data about the known focal adhesion-related kinases, and we focus on three topics in which they deserve great interest: neuroendocrine-immune interactions, developmental biology, and proliferative diseases.
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