Morphological changes in dental enamel after fluoride gel application in vitro
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Published on: March 29, 2018
1Bulgarian Academy of Sciences, Institute of Experimental Morphology and Anthropology, Department of Pediatric Dentistry, Faculty of Dentistry, Higher Medical Institute, Plovdiv, Bulgaria.
Introduction:
The investigations of in vitro models precede the clinical studies. Using these studied we can investigate the effect upon the enamel of different agents for local application.
Aim:
The purpose of this study was to investigate the ultrastructural changes in a normal and partially demineralized enamel after 0.42% fluoride gel application in vitro using scanning electron microscopy.
Material And Methods:
The experiment was performed on 20 premolars extracted for orthodontic indications. Symmetrical specimens were prepared, as one half served as a control, while the other one was treated with fluoride gel. The specimens were examined with electron microscope at different magnifications.
Results:
The findings show that fluoride gel applications affect the processes of mineralization and remineralization.
Conclusions:
This gives us the ground for applying fluoride gel in the clinical practice for prevention and treatment of caries incipiens.
