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[Testicular seminoma and multifocal aseptic osteonecrosis following chemotherapy]
1Service d'oncologie médicale, centre Antoine-Lacassagne, 33, avenue de Valombrose, 06189 Nice, France. magne@unice.fr
Introduction:
Multifocal osteonecrosis has a wide variety of etiologies, but in the cancer patient several risk factors could have a synergic effect (chemotherapy, radiotherapy, corticosteroid, metabolism disorder).
Exegesis:
A patient with testicular seminoma receiving cisplatin-based chemotherapy and short-term corticosteroid developed multifocal osteonecrosis. Early diagnosis of osteonecrosis is important to prevent orthopedic complications.
Conclusion:
Cisplatin could represent one of the possible etiologies of multifocal osteonecrosis. Magnetic resonance imaging has a high sensitivity and specificity in the diagnosis of osteonecrosis and should be used when this condition is suspected.