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Published on: November 17, 2014
International outpatient parenteral antimicrobial therapy
1University of Washington, Seattle, USA.
International Journal of Clinical Practice. Supplement
|February 24, 2001
Summary
Outpatient parenteral antimicrobial therapy (OPAT) practices differ worldwide due to cultural and economic factors. Variations in resources and therapy administration impact hospital stays and antimicrobial resistance, necessitating further research.
Area of Science:
- Infectious Diseases
- Health Services Research
- Global Health
Background:
- Outpatient parenteral antimicrobial therapy (OPAT) shows significant international variation.
- Cultural and economic factors influence OPAT practices and resource availability.
- Disparities exist in outpatient intravenous therapy infrastructure, such as infusion clinics.
Purpose of the Study:
- To explore the global variations in outpatient parenteral antimicrobial therapy (OPAT).
- To examine the relationship between OPAT practices, healthcare resources, and antimicrobial resistance.
- To highlight differences in intravenous versus intramuscular antimicrobial administration across countries.
Main Methods:
- Comparative analysis of international OPAT guidelines and practices.
- Review of healthcare system resources and economic factors influencing OPAT.
- Examination of antimicrobial usage patterns, including ceftriaxone, and resistance rates.
Main Results:
- Significant differences in OPAT duration, hospital stay length, and outpatient resource availability were observed globally.
- China has a high prevalence of infusion clinics, while the UK has scarce resources.
- Italy shows higher use of intramuscular ceftriaxone and lower antimicrobial resistance compared to other European nations, despite high ceftriaxone use in the US.
Conclusions:
- International OPAT practices are highly variable, influenced by economic and cultural contexts.
- The availability of outpatient resources significantly impacts hospital stay duration.
- Further research is needed to understand the factors contributing to lower antimicrobial resistance in certain regions, potentially linked to OPAT strategies.
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