Retinal vascular lesions in two patients with prolapsed mitral valve leaflets

Area of Science:

• Ophthalmology
• Cardiology
• Vascular Biology

Background:

• The prolapsed mitral valve (PMV) syndrome is a common cardiac condition.
• Retinal vascular lesions can have various underlying causes.
• A potential link between PMV and ocular vascular events requires further investigation.

Purpose of the Study:

• To describe the association between prolapsed mitral valve syndrome and retinal vascular lesions.
• To highlight clinical findings in patients with both conditions.

Main Methods:

• Case report of two patients with retinal vascular lesions and cardiac auscultation findings.
• Clinical examination including cardiac auscultation and funduscopic evaluation.
• Review of relevant medical literature.

Main Results:

• Two patients with PMV syndrome presented with distinct retinal vascular pathologies.
• Patient 1: Inferonasal arteriolar branch occlusion due to embolization.
• Patient 2: Central retinal vein occlusion with hemorrhages, glial proliferation, and neovascularization.

Conclusions:

• The prolapsed mitral valve syndrome may be associated with significant retinal vascular lesions.
• These findings suggest a potential embolic or other vascular mechanism linking PMV to ocular complications.
• Further research is warranted to elucidate the pathophysiology and clinical implications.