Related Experiment Video
Updated: Sep 29, 2026

Probiotic Studies in Neonatal Mice Using Gavage
Published on: January 27, 2019
[The use of biological preparations for correction of microbial status in pregnant women]
O V Korshunova1, L I Kafarskaia, B A Efimov
1Russian State Medical University, Institute of Medico-Social Rehabilitation, Research Institute of Immunology, Moscow, Russia.
Abstract:
15 pregnant women with pregnancy lasting 28-32 weeks, whose medico-laboratory data (the positive result of the amino test, high pH value and the detection of "key" cells) suggested the presence of bacterial vaginosis, were placed under observation. The bacteriological study of vaginal microflora in all these women revealed pronounced disturbances simultaneously with the development of intestinal dysbacteriosis. The local application of the bacterial preparation "Zhlemik" containing freeze-dried live lactic acid bacteria of vaginal origin and the oral administration of lactic acid bifidumbacterin containing live bifidobacteria of intestinal origin permitted the successful restoration of vaginal and intestinal microbiocenosis. The capacity of biotherapeutic preparations for inducing non-specific immunostimulation led to a significant rise in the levels of IgA, IgM and IgG in vaginal secretions.
Related Concept Videos
Microorganisms in Medicine and Therapeutics
Methods for Controlling Microbial Growth
Biological Methods for Microbial Control
Development of Human Microbiota
Development of the Oral Microbiota
Microbiota Modulation by Antibiotics

