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Updated: Aug 9, 2026

Assessing Therapeutic Angiogenesis in a Murine Model of Hindlimb Ischemia
Published on: June 8, 2019
Outcomes with plantar bypass for limb-threatening ischemia
S P Roddy1, R C Darling, B B Chang
1Institute for Vascular Health and Disease, Albany Medical College, NY 12208, USA.
Plantar artery bypass offers a viable alternative to amputation for patients with critical limb ischemia and limited options. Successful bypass surgery can lead to excellent limb salvage rates, especially when patency is maintained postoperatively.
Area of Science:
- Vascular Surgery
- Reconstructive Surgery
- Limb Salvage Procedures
Background:
- Severely diseased infrageniculate arteries, limited runoff, and tissue loss often lead to primary amputation in patients.
- Alternative revascularization strategies are crucial for limb salvage in complex cases.
Purpose of the Study:
- To review the experience and outcomes of plantar artery revascularization in patients where other bypass options are not feasible.
- To evaluate the safety, efficacy, and limb salvage potential of plantar artery bypass as an alternative to primary amputation.
Main Methods:
- Prospective data collection of patients undergoing infrainguinal bypass to the plantar artery over a 3-year period.
- Analysis of indications, patient demographics, length of stay, surgical outcomes, and bypass patency.
Main Results:
- Plantar artery bypass was identified as a safe and reasonable alternative to primary amputation.
- Excellent limb salvage rates were achieved, contingent upon maintaining bypass patency within the initial 30 postoperative days.
Conclusions:
- Plantar artery bypass is a valuable option for limb salvage in select patients with critical limb ischemia.
- Maintaining early postoperative bypass patency is critical for successful limb salvage outcomes.
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