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Updated: Aug 19, 2026
Method of Isolated Ex Vivo Lung Perfusion in a Rat Model: Lessons Learned from Developing a Rat EVLP Program
Published on: February 25, 2015
Heart and lung preservation for transplantation
C B Huddleston1, E N Mendeloff
1Department of Surgery, Division of Cardiothoracic Surgery, Washington University School of Medicine, St Louis, Missouri, USA. huddlestonc@msnotes.wustl.edu
Abstract:
Since the beginning of transplantation the search for optimal means of organ preservation has been ongoing. One of the major causes of death early following heart or lung transplantation is graft failure. Factors that play a role in this problem include recipient and donor issues, but clearly procurement techniques and preservation solutions are important. This article summarizes the history, current clinical practice, and research devoted to heart and lung preservation for transplantation.
