Related Experiment Video
Updated: Sep 14, 2026

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse
Published on: March 8, 2013
Does anybody know how we should measure Doppler parameters in lymph nodes?
S S Ho1, C Metreweli, A T Ahuja
1Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, Shatin, N.T., Hong Kong.
Aim:
To show how currently described techniques confuse interpretation of Doppler indices in lymph node characterization.
Materials And Methods:
The Doppler indices [resistivity index (RI) and pulsatility index (PI)] were obtained in 35 malignant lymph nodes by colour duplex sonography. Each node was sampled at eight different sites. Data were analysed using our own method, and methods employed in six previous studies.
Results:
Restistivity index values varied between 0.69 and 0.88 and PI values ranged from 1.28 to 2.34. All but two methods produced different resistance indices (P < 0.05).
Conclusion:
Conflicting results are obtained analysing the same data using different methods. Standardized techniques should be agreed and employed in future studies.
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