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Association between polycystic ovary and fibrocystic breast disease
R D'Amelio1, M Farris, S Grande
11st Institute of Obstetrics and Gynaecology, University of Rome 'La Sapienza', Rome, Italy.
Objective:
The aim of this study was to assess whether or not there was an association between a polycystic ovary (PCO) and fibrocystic breast disease based on ultrasound findings, both pelvic and mammographic.
Design:
Prospective case-control study.
Population:
Women aged between 18 and 30 years not using oral contraceptives attending the outpatient ultrasound clinic from January 1996 to December 1998.
Main Outcome:
Confirm the association between PCO and fibrocystic breast disease.
Results:
According to the ultrasound findings, women were allocated to three groups: 351 out of 456 showed normal-appearing ovaries (group A), 93 had polycystic-appearing ovaries/PCO (group B) and 12 had PCO syndrome (group C). In group A, 24 (6.83%) women showed breast pathology. In group B, there was an association between PCO and breast pathology in 53 (56.98%) women, while in group C it was noted in 11 out of 12 (91%).
Conclusion:
This study showed a significant association between PCO and benign pathology. This should encourage the performance of a screening breast sonography on women with PCO.