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Updated: Oct 9, 2026

An Immature Murine Model of Reversible Unilateral Ureteral Obstruction
Published on: April 4, 2025
Vesicoureteral reflux in the early stage of spinal cord injury: a retrospective study
1Department of Urology, National Rehabilitation Center for the Disabled, Tokorozawa, Japan.
Study Design:
A retrospective study.
Objectives:
To investigate the risk factors of vesicoureteral reflux in the early stage of spinal cord injury.
Setting:
Japan.
Methods:
Urological evaluation, including cystography and urodynamic study was performed in patients in the early stage of spinal cord injury. The patients were divided into two groups. Group 1 included 13 patients with vesicoureteral reflux. Group 2 included 97 patients without vesicoureteral reflux. We compared Group 1 and Group 2 regarding bladder deformation, the level of spinal cord injury, bladder behaviour, bladder compliance, high urethral closure pressure and method of urine evacuation.
Results:
The patients injured between Th10 and L2 showed a significantly higher incidence of vesicoureteral reflux than those injured in other areas (P<0.01). Furthermore, bladder compliance among patients with vesicoureteral reflux tended to be low. Other factors showed no differences between patients with and without vesicoureteral reflux.
Conclusion:
Injuries between Th10 and L2 involve the sympathetic nervous system. Patients with such injuries often exhibited vesicoureteral reflux in the early stage of spinal cord injury.
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