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Updated: Aug 15, 2026

In vitro Cell Culture Model for Toxic Inhaled Chemical Testing
Published on: May 8, 2014
Toxic exposures
1Department of Pediatrics, New York University School of Medicine, NYU Medical Center, 540 First Avenue, New York, NY 10016, USA.
Abstract:
Adolescence is a time of immense physical and social change. Risk-taking behavior is commonplace and often includes experimentation with various illicit drugs. Toxic ingestions remain a significant medical problem in this population. The major objective of this review is to provide an overview of the more common toxic exposures in adolescents. A framework is presented for understanding some of the factors that result in substance abuse in adolescents. Signs, symptoms and clinical manifestations of commonly abused drugs are presented along with general approaches to management of acute overdose. As the population of adolescents with underlying heart disease continues to grow, it is important for primary care providers to individualize treatment of adolescents with congenital or acquired heart disease. The impact of pre-existing cardiac disease is briefly reviewed.
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