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Related Experiment Videos

A large new Streptococcus bacteriophage.

H W Ackermann, T Caprioli, S S Kasatiya

    Canadian Journal of Microbiology
    |April 1, 1975
    PubMed
    Summary

    Phage VD13, active against group D streptococci, has a large head and long tail. This double-stranded DNA virus exhibits rare head malformations, including giant heads likely containing DNA.

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    Area of Science:

    • Microbiology
    • Virology
    • Bacteriology

    Background:

    • Bacteriophages are viruses that infect bacteria.
    • Group D streptococci are a significant group of bacteria.
    • Phage morphology and genetics are crucial for understanding viral behavior.

    Purpose of the Study:

    • To characterize the morphology and properties of bacteriophage VD13.
    • To investigate the unusual head malformations observed in phage VD13.
    • To determine the host range and genetic material of phage VD13.

    Main Methods:

    • Morphological analysis using electron microscopy.
    • DNA extraction and characterization.
    • Host range determination through plaque assays.

    Main Results:

    • Phage VD13 has a large, elongated head and a long, non-contractile tail.
    • The phage infects group D streptococci and contains double-stranded DNA.
    • Rare head malformations, including polymorphic mottled structures and giant heads, were observed.

    Conclusions:

    • Phage VD13 is a unique bacteriophage with distinct morphological features.
    • The observed head malformations may be related to DNA packaging or replication.
    • Further studies are warranted to elucidate the genetic basis of these malformations.

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