Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Relationship between leucine oxidation and oxygen consumption during steady-state exercise.

L S Lamont1, A J McCullough, S C Kalhan

  • 1Exercise Science Program, the University of Rhode Island, Kingston, RI 02881, USA. lla4983u@postoffice.uri.edu

Medicine and Science in Sports and Exercise
|February 27, 2001
PubMed
Summary

During steady-state exercise, whole-body leucine oxidation moderately correlates with energy expenditure. Approximately half of the variance in leucine oxidation during exercise is explained by oxygen consumption.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hepatobiliary and Pancreatic: Mauriac syndrome: A rare cause of elevated liver enzymes.

Journal of gastroenterology and hepatology·2018
Same author

Safety and efficacy of bariatric surgery in patients with advanced fibrosis.

International journal of obesity (2005)·2016
Same author

Lack of Influence of the Menstrual Cycle on Blood Lactate.

The Physician and sportsmedicine·2016
Same author

Effect of multi-nutrient insufficiency on markers of one carbon metabolism in young women: response to a methionine load.

European journal of clinical nutrition·2015
Same author

Pretest variables that improve the predictive value of exercise testing in women.

The Journal of sports medicine and physical fitness·2014
Same author

Prematurity and programming: contribution of neonatal Intensive Care Unit interventions.

Journal of developmental origins of health and disease·2014

Area of Science:

  • Exercise Physiology
  • Nutritional Biochemistry

Background:

  • Leucine is a crucial branched-chain amino acid involved in protein synthesis and energy metabolism.
  • Understanding leucine's role in energy expenditure during exercise is vital for optimizing athletic performance and nutritional strategies.

Purpose of the Study:

  • To investigate the relationship between whole-body leucine oxidation and oxygen consumption during steady-state exercise.
  • To determine if leucine oxidation responds to increased energy demands during physical activity.

Main Methods:

  • Sixteen healthy participants (7 women, 9 men) underwent stable isotope infusion of leucine and lysine.
  • Participants engaged in 60 minutes of moderate-intensity, steady-state exercise.

Main Results:

Related Experiment Videos

  • Leucine oxidation significantly increased, while nonoxidative leucine disposal decreased during exercise (P < 0.05).
  • A modest, significant relationship (R = 0.69, P < 0.003) was found between leucine oxidation and steady-state oxygen consumption.
  • Whole-body oxygen consumption explained approximately 49% of the variance in whole-body leucine oxidation during exercise.

Conclusions:

  • Whole-body leucine oxidation during exercise is only partially influenced by energy demands in humans with controlled dietary intake.
  • These findings suggest that while energy expenditure plays a role, other factors also regulate leucine metabolism during physical activity.