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Published on: March 21, 2013
Clinical experience of a new rate drop response algorithm in the treatment of vasovagal and carotid sinus syncope
J B Johansen1, R S Bexton, E H Simonsen
1Department of Cardiology, Odense University Hospital, Denmark. brock@med.ou.dk
Insights
Dual chamber pacing with the rate drop response algorithm effectively manages vasovagal syncope and carotid sinus syndrome. This advanced pacing technology rapidly detects and treats dangerous heart rate drops, preventing fainting episodes.
Area of Science:
- Cardiology
- Biomedical Engineering
Background:
- Dual chamber pacing is beneficial for conditions causing sudden heart rate drops, such as vasovagal syncope and carotid sinus syndrome.
- Newer pacemaker algorithms aim for faster detection and intervention during bradycardic events.
Observation:
- Two case reports detail the use of the rate drop response (RDR) algorithm in Medtronic Kappa pacemakers.
- A young woman with vasovagal syncope experienced complete syncope abolition after RDR algorithm implantation.
- An older man with coronary artery disease and asystole-induced presyncope became asymptomatic with RDR algorithm pacing.
Findings:
- The RDR algorithm demonstrated effective and rapid intervention in both vasovagal syncope and carotid sinus syndrome cases.
- Pacemaker implantation with the RDR algorithm successfully resolved syncope and presyncope in the presented patients.
- The RDR algorithm's performance was validated through clinical observation and patient outcomes.
Implications:
- The RDR algorithm represents a significant advancement in managing neurally mediated syncope and bradyarrhythmias.
- Recommendations for optimizing RDR algorithm use in clinical practice are discussed.
- This technology offers improved quality of life for patients suffering from recurrent syncope due to heart rate abnormalities.
Abstract:
Dual chamber pacing has proven beneficial in patients with sudden drops in heart rate as seen in vasovagal syncope and carotid sinus syndrome. Newer algorithms for faster detection of an insidious drop in heart rate and short lasting intervention pacing at a high rate, as in the rate drop response algorithm in the Medtronic Kappa series of pacemakers, might improve the effect of pacing. Two case reports, that demonstrate the use of these rate drop response algorithms, are presented. A 24-year-old woman with recurrent episodes of syncope and repeated tilt-table tests with vasovagal cardioinhibitory outcomes had a Medtronic Kappa 400 pacemaker implanted. Syncope was abolished during repeat tilt-table testing following pacemaker implantation and proper functioning of the rate drop response algorithm. The patient has been free of syncope during follow-up apart from a single episode that occurred due to neglect of vasovagal warning symptoms. A 52-year-old man with coronary artery disease developed recurrent blackouts. Carotid sinus massage resulted in 5.5 s of asystole and presyncope. A Medtronic Kappa 700 pacemaker with a rate drop response algorithm was implanted and the patient became asymptomatic. The rate drop response algorithm is discussed in detail based upon the case reports, and recommendations are given for the use of this algorithm in patients with vasovagal syncope and carotid sinus syndrome.
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