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Internal jugular vein thrombosis after ovarian stimulation
B Belaen1, K Geerinckx, P Vergauwe
1Department of Gynecology-Fertility, C.A.Z.K.Groeninghe Campus Sint-Niklaas, Houtmarkt 33, Kortrijk, Belgium.
Human Reproduction (Oxford, England)
|March 3, 2001
Summary
Thrombosis is a rare complication of ovarian stimulation for IVF. This case highlights internal jugular vein thrombosis in a patient without typical risk factors, successfully treated with heparin.
Area of Science:
- Reproductive Medicine
- Vascular Medicine
- Thrombosis Research
Background:
- Ovarian stimulation for in vitro fertilization (IVF) can rarely lead to thromboembolic events.
- Thrombosis is often associated with ovarian hyperstimulation syndrome (OHSS) or inherited clotting disorders.
- Identifying risk factors for thrombosis post-ovarian stimulation is crucial for patient management.
Observation:
- A case of internal jugular vein thrombosis occurred after gonadotropin stimulation for IVF.
- The patient presented with thrombosis despite negative screening for OHSS and hereditary hypercoagulability.
- This suggests potential alternative mechanisms or unidentified risk factors for thrombosis.
Findings:
- Internal jugular vein thrombosis is a rare but serious complication of ovarian stimulation.
- Absence of typical risk factors (OHSS, hereditary hypercoagulability) complicates diagnosis and prevention.
- Low molecular weight heparin proved effective in treating the thrombosis.
Implications:
- This case underscores the importance of vigilance for thromboembolic events even in low-risk patients undergoing ovarian stimulation.
- Further research may be needed to elucidate non-traditional risk factors for thrombosis in this context.
- Successful management with anticoagulation allowed for a positive pregnancy outcome, highlighting treatment efficacy.