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Updated: Jul 17, 2026

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Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
Published on: December 2, 2022
Amelanotic corneal melanoma after a blast injury
1Department of Ophthalmology, University of California, San Francisco, CA, USA.
American Journal of Ophthalmology
|March 3, 2001
Abstract
Purpose:
To report a case of a corneal melanoma after trauma.
Methods:
Case report.
Results:
A 68-year-old man sustained an ocular injury from a blast furnace explosion in 1958. In 1998, he underwent a penetrating keratoplasty for a corneal scar. Histologic examination and cell markers of the host button revealed intrastromal and subepithelial melanoma. No clinical or microscopic evidence of adjacent conjunctival or uveal melanoma was found.
Conclusion:
Melanoma of the cornea can present as a stromal opacity after trauma.

