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Updated: Jul 29, 2026

Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate
Published on: September 11, 2013
Spontaneous regression and disappearance of subclinical rhegmatogenous retinal detachment
1University of California School of Medicine, Los Angeles, California, USA.
Purpose:
To report spontaneous regression and disappearance of subclinical rhegmatogenous retinal detachment.
Methods:
Case reports.
Results:
Three separate areas of subclinical retinal detachment in two eyes of two patients were followed without treatment for 35 years (Case 1) and 28 years (Case 2). The three areas of subclinical retinal detachment spontaneously regressed and disappeared. There has been no recurrence of subclinical retinal detachment in Case 1 for 12 years and 14 years, and in Case 2 for 12 years.
Conclusion:
Subclinical retinal detachment can show spontaneous regression and disappearance as its natural outcome when observed without intervention.

