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Chemokines in lymphopoiesis and lymphoid organ development
1Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, 513 Parnassus Avenue, San Francisco, CA 94143-0414, USA. ansel@itsa.ucsf.edu
Current Opinion in Immunology
|March 3, 2001
Abstract:
An important role has emerged for chemokines in regulating the distribution of progenitor cells during hematopoietic cell development. As well as recruiting cells, chemokines promote cell retention and cytokine expression. Furthermore, chemokines have been found to have an inductive function in secondary lymphoid organ development.