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Related Experiment Videos

Cardiac output-based versus empirically programmed AV interval--how different are they?

E Crystal1, I E Ovsyshcher

  • 1Arrhythmia Service, Department of Cardiology, and Faculty of Health Sciences, Ben Gurion University of the Negev, Beer-Sheva, Israel.

Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology
|March 7, 2001
PubMed
Summary

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Optimizing the atrioventricular (AV) interval in dual chamber pacemakers using cardiac output measurements improves heart function. This method enhances cardiac output by 12% compared to empirical programming in patients with AV block.

Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Medical Devices

Background:

  • Dual chamber pacemakers are crucial for managing atrioventricular (AV) block.
  • The programming of the AV interval significantly impacts cardiac function.
  • Empirical programming may not always achieve optimal hemodynamic performance.

Purpose of the Study:

  • To compare the efficacy of empirically programmed AV intervals versus cardiac output-based programming.
  • To determine if optimizing AV intervals can improve cardiac output in patients with dual chamber pacemakers.

Main Methods:

  • Nineteen patients with dual chamber pacemakers for AV block were studied.
  • Cardiac output was measured using impedance cardiography.
  • AV intervals were systematically adjusted to identify optimal settings based on cardiac output.

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Main Results:

  • Cardiac output-based programming improved cardiac output in 84% of patients.
  • The maximal achievable cardiac output increased by an average of 12% (P < 0.001) compared to empirical settings.
  • Empirically programmed AV intervals may compromise cardiac hemodynamics.

Conclusions:

  • Empirical AV interval programming in dual chamber pacemakers can be suboptimal.
  • Serial cardiac output measurements are effective for selecting optimal AV intervals.
  • This approach can enhance hemodynamic function in patients with AV block.