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Non-fermenters in urinary tract infection
M L Kaushal1, P S Grover, M L Gupta
1IG Medical College, Shimla.
The Journal of the Association of Physicians of India
|March 7, 2001
Summary
Non-fermenting gram-negative bacteria (NFGNB) were identified in urine samples. Most NFGNB isolates showed sensitivity to norfloxacin and ofloxacin, but resistance to penicillin and tetracycline.
Area of Science:
- Clinical Microbiology
- Infectious Diseases
- Bacteriology
Background:
- Non-fermenting gram-negative bacteria (NFGNB) are significant opportunistic pathogens.
- Urinary tract infections (UTIs) are common, and NFGNB can cause complicated UTIs.
Purpose of the Study:
- To isolate and identify NFGNB from urine samples.
- To determine the antibiotic susceptibility patterns of isolated NFGNB.
Main Methods:
- Bacterial isolates were obtained from 7,784 urine samples.
- Isolation and identification of NFGNB were performed.
- Antibiotic susceptibility testing was conducted using various agents.
Main Results:
- Sixty-four NFGNB strains were isolated (4.4% of total isolates).
- Pseudomonas aeruginosa was the most prevalent species (67.2%).
- High sensitivity was observed for norfloxacin and ofloxacin (50-88.8%), while resistance to penicillin and tetracycline was noted in all isolates.
Conclusions:
- NFGNB are found in urine samples, with P. aeruginosa being the most common.
- Fluoroquinolones like norfloxacin and ofloxacin are effective against these isolates.
- Antibiotic resistance patterns highlight the need for judicious antibiotic use in UTIs caused by NFGNB.