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Synthesis and monoamine transporter affinity of 3beta-(4-(2-pyrrolyl)phenyl)-8-azabicycl
1Department of Chemistry, State University of New York at Buffalo, 14260-3000, USA. hdavies@acsu.buffalo.edu
Bioorganic & Medicinal Chemistry Letters
|March 7, 2001
Abstract:
3Beta-(5-indolyl)-8-azabicyclo[3.2.1]octanes display potent binding affinity for both the dopamine and serotonin transporters, while certain 3beta-(4-(2-pyrrolyl)phenyl)-8-azabicyclo[3.2.1]octanes selectively bind to the serotonin transporter.