Related Experiment Video
Updated: Jul 11, 2026

Establishment of a Clinic-based Biorepository
Published on: May 29, 2017
Stereotactic core biopsy breast and blood cell by-products: a source of material for molecular genetics
P C Stomper1, C C Stewart, D L Stoler
1Departments of Diagnostic Imaging, Roswell Park Cancer Institute, School of Medicine and Biomedical Sciences, SUNY, Elm and Carlton Sts, Buffalo, NY 14263, USA. Paul.Stomper@roswellpark.org
Abstract:
Stereotactic core biopsy washings and blood drop samples, routinely discarded by-products, provide satisfactory fresh cellular material for flow cytometry and molecular genetics microsatellite polymerase chain reaction (PCR) analysis for detection of loss of DNA alleles (loss of heterozygosity). Cytokeratin-positive (epithelial) cells from the core biopsy washings were sorted by means of flow cytometry prior to PCR analysis. DNA allele loss was detected in benign breast epithelial cells in three (20%) of 15 patients.
More Related Videos
05:49Use of Magnetic Resonance Imaging and Biopsy Data to Guide Sampling Procedures for Prostate Cancer Biobanking
Published on: October 10, 2019
06:42Optimization of Breast Biopsy and Mastectomy Sample Collection Procedures for Biobanking, Personalized Medicine, and Research Applications
Published on: September 2, 2025