Lipoprotein(a), Friedewald formula, and NCEP guidelines. National Cholesterol Education Program

The Friedewald low-density lipoprotein cholesterol formula, which is commonly used in clinical chemistry laboratories, comprises both low-density lipoprotein and lipoprotein(a) cholesterol. This confounder must be recognized and appropriately corrected when dealing with subjects with high plasma lipoprotein(a) levels.