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Evaluation of long-term survival after successful percutaneous coronary intervention among patients with chronic

H H Ting1, N K Tahirkheli, P B Berger

  • 1Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA.

The American Journal of Cardiology
|March 7, 2001
PubMed

Insights

Percutaneous coronary intervention outcomes are worse for dialysis and chronic renal failure patients. These groups experienced significantly higher 1-year all-cause and cardiac mortality compared to controls.

Area of Science:

  • Nephrology
  • Cardiology
  • Interventional Cardiology

Background:

  • Patients with chronic renal failure (CRF) and end-stage renal disease requiring dialysis have complex cardiovascular risk profiles.
  • Long-term outcomes following percutaneous coronary intervention (PCI) in these high-risk populations are not well-defined.

Purpose of the Study:

  • To evaluate and compare the long-term clinical outcomes of percutaneous coronary intervention (PCI).
  • To assess mortality rates in patients with chronic renal failure (CRF) and those on dialysis undergoing PCI.

Main Methods:

  • Retrospective study comparing outcomes of PCI.
  • Patient groups included: control, chronic renal failure (CRF) (serum creatinine ≥ 3.0 mg/dl), and dialysis patients.
  • One-year all-cause and cardiac mortality were the primary endpoints.

Main Results:

  • One-year all-cause mortality was 2.9% (control), 16.2% (CRF), and 14.1% (dialysis).
  • One-year cardiac mortality was 1.9% (control), 15.2% (CRF), and 10.0% (dialysis).
  • Both CRF and dialysis groups showed substantially higher mortality rates compared to the control group.

Conclusions:

  • Percutaneous coronary intervention (PCI) in patients with chronic renal failure (CRF) or on dialysis is associated with significantly increased short-term mortality.
  • These findings highlight the heightened cardiovascular risk and poorer prognosis in renal impairment patients undergoing PCI.
  • Further research into risk mitigation strategies for these vulnerable populations is warranted.

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