CYP3A genetics in drug metabolism

Variability in hepatic expression of organic anion transporter 7/SLC22A9, a novel pravastatin uptake transporter: impact of genetic and regulatory factors.

The pharmacogenomics journal·2015

Impact of the serum- and glucocorticoid-inducible kinase 1 on platelet dense granule biogenesis and secretion.

Journal of thrombosis and haemostasis : JTH·2015

Tamoxifen metabolism predicts drug concentrations and outcome in premenopausal patients with early breast cancer.

The pharmacogenomics journal·2014

CYP2D6 genotype and adjuvant tamoxifen: meta-analysis of heterogeneous study populations.

Clinical pharmacology and therapeutics·2013

Differential effects of clinically used derivatives and metabolites of artemisinin in the activation of constitutive androstane receptor isoforms.

British journal of pharmacology·2012

Human pregnane X receptor genotype of the donor but not of the recipient is a risk factor for delayed graft function after renal transplantation.

Clinical pharmacology and therapeutics·2012

Emergence and spread of Plasmodium falciparum PX1 polymorphisms associated with decreased susceptibility to antimalarials in Uganda.

Nature medicine·2026

Histological aging signatures for monitoring tissue-specific aging and disease.

Nature medicine·2026

How to build an AI-driven digital organism.

Nature medicine·2026

First-line PD-1/VEGF bispecific antibody plus chemotherapy in triple-negative breast cancer: a phase 2 trial.

Nature medicine·2026

Acquired resistance to the RAS(ON) multi-selective inhibitor daraxonrasib guides rational combination therapy strategies in pancreatic cancer.

Nature medicine·2026

Decade-long persistence of CD19 CAR T cells in B cell lymphomas.

Nature medicine·2026

Genetic and epigenetic determinants of cytochrome P450 activity in psychopharmacology: from pharmacogenetics to functional pharmacogenomics.

Progress in neuro-psychopharmacology & biological psychiatry·2026

Burden of health comorbidities and associated health care costs in the Australian genetics of depression study using the medication-based Rx-risk comorbidity index.

Journal of affective disorders·2026

Benzodiazepine Prescribing in Delirium Diagnosis: National Data on Clinical Practice.

Journal of the Academy of Consultation-Liaison Psychiatry·2026

Mechanistic study on the species differences in metabolism and excretion pathways of ivarmacitinib between humans and rats.

Drug metabolism and disposition: the biological fate of chemicals·2026

Comment on "Network pharmacology and experimental validation reveal inhibition of the JAK2/STAT3 pathway by hydrogen sulfide in diabetic cardiomyopathy".

International immunopharmacology·2026

Structure-function relationships of pectic Fibers from pitaya Peel in astaxanthin-loaded emulsion systems.

Food chemistry·2026

Related Experiment Videos

CYP3A genetics in drug metabolism

Related Concept Videos

Variability in hepatic expression of organic anion transporter 7/SLC22A9, a novel pravastatin uptake transporter: impact of genetic and regulatory factors.

Impact of the serum- and glucocorticoid-inducible kinase 1 on platelet dense granule biogenesis and secretion.

Tamoxifen metabolism predicts drug concentrations and outcome in premenopausal patients with early breast cancer.

CYP2D6 genotype and adjuvant tamoxifen: meta-analysis of heterogeneous study populations.

Differential effects of clinically used derivatives and metabolites of artemisinin in the activation of constitutive androstane receptor isoforms.

Human pregnane X receptor genotype of the donor but not of the recipient is a risk factor for delayed graft function after renal transplantation.

Emergence and spread of Plasmodium falciparum PX1 polymorphisms associated with decreased susceptibility to antimalarials in Uganda.

Histological aging signatures for monitoring tissue-specific aging and disease.

How to build an AI-driven digital organism.

First-line PD-1/VEGF bispecific antibody plus chemotherapy in triple-negative breast cancer: a phase 2 trial.

Acquired resistance to the RAS(ON) multi-selective inhibitor daraxonrasib guides rational combination therapy strategies in pancreatic cancer.

Decade-long persistence of CD19 CAR T cells in B cell lymphomas.

Genetic and epigenetic determinants of cytochrome P450 activity in psychopharmacology: from pharmacogenetics to functional pharmacogenomics.

Burden of health comorbidities and associated health care costs in the Australian genetics of depression study using the medication-based Rx-risk comorbidity index.

Benzodiazepine Prescribing in Delirium Diagnosis: National Data on Clinical Practice.

Mechanistic study on the species differences in metabolism and excretion pathways of ivarmacitinib between humans and rats.

Comment on "Network pharmacology and experimental validation reveal inhibition of the JAK2/STAT3 pathway by hydrogen sulfide in diabetic cardiomyopathy".

Structure-function relationships of pectic Fibers from pitaya Peel in astaxanthin-loaded emulsion systems.

Related Experiment Videos

CYP3A genetics in drug metabolism

Related Concept Videos

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