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Updated: Jul 26, 2026

Assessment of Endothelial Cell Migration After Exposure to Toxic Chemicals
07:07

Assessment of Endothelial Cell Migration After Exposure to Toxic Chemicals

Published on: July 10, 2015

Methotrexate causes apoptosis in postmitotic endothelial cells.

C J Merkle1, I M Moore, B S Penton

  • 1College of Nursing, Department of Physiology, University of Arizona, Tucson, AZ 85721, USA. cmerkle@nursing.arizona.edu

Biological Research for Nursing
|March 10, 2001
PubMed
Summary

Methotrexate (MTX) chemotherapy can harm endothelial cells. This study found MTX induces apoptosis, or programmed cell death, in these cells, suggesting a mechanism for MTX-related toxicity.

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