[Mitochondrial DNA sequence variations of Zhuang ethnic group in Guangxi]

The mtDNA hypervariable segment I sequences (515bp) were sequenced in 83 Zhuangs from Gunngxi Province, with the aim to learn more about the origin and genetic structure of the current Zhuangs. 66 haplotypes were identified in the samples, with 71 sites showing polymorphism. Phylogenetic analysis of the 66 haplotypes suggests that there are geographic differentiation in current Zhuangs, and those from the 4 geographic regions (Nanning, Hechi, Baise and Liuzhou) have different distribution frequencies in the cluster I, II and III in the tree. More than 50% individuals from Liuzhou and Hechi converge into cluster II, while those from Nanning and Baise have high frequency in cluster I. Combined with the analysis of the reported data, the Zhuang ethnic group shows remote affinity to those from North China, whereas it is close to those in South China. The frequencies of the radiation groups in Zhuangs, together with the phylogenetic relationship of the Zhuang ethnic group in the tree suggest that the Zhuang is a typical south population.