Related Experiment Video

Updated: Aug 8, 2026

Identification of Intracellular Signaling Events Induced in Viable Cells by Interaction with Neighboring Cells Undergoing Apoptotic Cell Death
09:18

Identification of Intracellular Signaling Events Induced in Viable Cells by Interaction with Neighboring Cells Undergoing Apoptotic Cell Death

Published on: December 27, 2016

Signaling through CD31 protects endothelial cells from apoptosis

P C Evans1, E R Taylor, P J Kilshaw

  • 1Molecular Immunology Programme, The Babraham Institute, Cambridge, UK.

Transplantation
|March 10, 2001
PubMed
Summary

Signaling through CD31 (platelet-endothelial cell adhesion molecule-1) protects endothelial cells from apoptosis. This process involves up-regulating protective genes like A20 and A1, crucial for long-term graft survival.

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