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Vilsmeier formylation of praziquantel: synthesis and application for polarographic assay
Die Pharmazie
|March 10, 2001
Abstract:
A simple and sensitive method for the polarographic determination of praziquantel (1) after derivatization using Vilsmeier formylation is described. The polarographically active compound obtained by this procedure has been separated, identified and prepared using N,N-dimethylformamide and phosphorus oxychloride.