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Spectrophotometric and HPLC determination of fleroxacin in tablets
L Milovanović1, V Kapetanović, G Popović
1Institute of Analytical, Inorganic and Physical Chemistry, Faculty of Pharmacy, University of Belgrade, Yugoslavia.
Die Pharmazie
|March 10, 2001
Abstract:
The paper describes and compares spectrophotometric and HPLC determination of fleroxacin in commercial tablets. The optimum conditions for spectrophotometric assay were found to be at pH < 3.5 (0.1 M HCl) at a wave length of 286 nm. HPLC analysis was carried out on a Beckman ODS 5 microns column in a pH 3 phosphoric acid solution (detector wave length 254 nm).