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[HOX genes in embryo- and phylogenesis]
1Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, 117871 Russia.
Ontogenez
|March 10, 2001
Summary
This review explores the structure and function of HOX gene protein products. It examines the link between the evolution of the HOX complex and morphological changes.
Area of Science:
- Developmental Biology
- Evolutionary Biology
- Genetics
Context:
- The HOX gene complex plays a crucial role in embryonic development.
- Understanding HOX gene function is key to deciphering developmental processes.
Purpose:
- To review the structure and function of HOX gene protein products.
- To explore the evolutionary relationship between the HOX complex and morphological evolution.
Summary:
- HOX genes encode transcription factors that regulate anterior-posterior patterning during development.
- Evolutionary analysis reveals conserved and divergent roles of HOX genes across species.
- The evolution of the HOX complex is intertwined with the emergence of diverse body plans.
Impact:
- Provides insights into the genetic basis of morphological evolution.
- Highlights the importance of HOX genes in developmental plasticity.
- Informed understanding of evolutionary developmental biology.