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Updated: Aug 14, 2026

Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage
10:34

Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage

Published on: August 30, 2020

[Behcet's disease manifested as a intracranial aneurysm]

S Rosenstingl1, E Dupuy, O Alves

  • 1Service d'angiohématologie clinique, hôpital Lariboisière, 2, rue Ambroise-Paré, 75010 Paris, France.

La Revue De Medecine Interne
|March 10, 2001
PubMed

Insights

Vascular complications, including rare intracranial aneurysms, are common in Behçet's disease. Endovascular treatment combined with immunosuppression offers a favorable outcome for posterior circulation aneurysms in this condition.

Area of Science:

  • Neurology
  • Vascular Surgery
  • Rheumatology

Background:

  • Vascular complications are frequent in Behçet's disease, predominantly venous but also arterial.
  • Arterial complications include stenosis, occlusions, and aneurysms, with a significant rupture risk.
  • Intracranial aneurysms are exceptionally rare in Behçet's disease, with only ten prior cases reported.

Observation:

  • A 36-year-old Armenian patient with Behçet's disease presented with subarachnoid hemorrhage due to a ruptured left superior cerebellar artery aneurysm.
  • This represents the first reported case of a Behçet's disease-associated posterior circulation aneurysm treated endovascularly.

Findings:

  • Endovascular treatment of the aneurysm was successfully performed.
  • The patient received immunosuppressive therapy including cyclophosphamide, corticoids, and colchicine.
  • A favorable 6-month follow-up was observed.

Implications:

  • Intracranial aneurysms, though rare, are a severe vascular complication of Behçet's disease.
  • Treatment requires endovascular or surgical intervention combined with immunosuppressive therapy and corticoids.
  • Colchicine is beneficial for preventing recurrences of arterial lesions in Behçet's disease.
Abstract

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