Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Memory-forming chemical reactions.

E D Roberson1, J D Sweatt

  • 1Division of Neuroscience, Baylor College of Medicine, Houston, TX 77030-3498, USA.

Reviews in the Neurosciences
|March 10, 2001
PubMed
Summary

Biological memory storage relies on chemical reactions. This review covers short-term (second messengers), long-term (stable molecules), and ultralong-term (mnemogenic) reactions across species.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU): Trial Satisfaction and Attitudes towards Future Clinical Trials.

The journal of prevention of Alzheimer's disease..·2024
Same author

<i>Tet1</i> Isoforms Differentially Regulate Gene Expression, Synaptic Transmission, and Memory in the Mammalian Brain.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2020
Same author

Comparison of sporadic and familial behavioral variant frontotemporal dementia (FTD) in a North American cohort.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2020
Same author

Active lifestyles moderate clinical outcomes in autosomal dominant frontotemporal degeneration.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2020
Same author

Progranulin haploinsufficiency causes biphasic social dominance abnormalities in the tube test.

Genes, brain, and behavior·2016
Same author

Age-related changes in Arc transcription and DNA methylation within the hippocampus.

Neurobiology of aging·2010

Area of Science:

  • Neuroscience
  • Molecular Biology
  • Biochemistry

Background:

  • Memory formation and storage are fundamental biological processes.
  • Understanding the molecular mechanisms of memory is crucial for neuroscience.
  • Existing research highlights diverse molecular players in memory consolidation.

Purpose of the Study:

  • To review the chemical reactions underlying biological memory storage.
  • To categorize memory-storing reactions based on their molecular kinetics and duration.
  • To provide a comprehensive overview of memory mechanisms in various organisms.

Main Methods:

  • Literature review of studies on memory formation in invertebrate and mammalian systems.
  • Analysis of biochemical pathways involved in synaptic plasticity and memory.
  • Classification of memory-related chemical reactions based on molecular turnover and stability.

Main Results:

  • Identified three primary types of memory-storing chemical reactions.
  • Short-term memory involves transient changes in second messenger levels.
  • Long-term and ultralong-term memory depend on stable molecular species and mnemogenic reactions, respectively, persisting despite molecular turnover.

Conclusions:

  • Chemical reactions are the fundamental basis of biological memory.
  • The duration of memory correlates with the stability and turnover rate of the involved molecular species.
  • Further research into mnemogenic reactions could unlock mechanisms for indefinite memory storage.

Related Experiment Videos