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Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria
14:04

Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria

Published on: May 8, 2013

[Drug resistance of Staphylococcus aureus strains, isolated from children with intestinal dysbacteriosis]

I V Nikolaeva1, V A Anokhin, V M Bondarenko

  • 1State Medical Uneversity, Kazan, Gamaleya Research Institute of Epidemiology and Microbiology, Moscow, Russia.

Zhurnal Mikrobiologii, Epidemiologii I Immunobiologii
|March 10, 2001
PubMed

Insights

Antibiotic resistance in Staphylococcus aureus strains from children with gut dysbiosis is significant, with many polyresistant and Methicillin-resistant S. aureus (MRSA) strains identified. Gut microflora suppression is a key risk factor for staphylococcal infections.

Area of Science:

  • Microbiology
  • Clinical Medicine
  • Infectious Diseases

Context:

  • Investigated antibiotic sensitivity of Staphylococcus aureus in children with large intestine dysbiosis.
  • High prevalence of polyresistant (44%) and Methicillin-resistant S. aureus (MRSA) (34.2%) strains observed in an outpatient setting.

Purpose:

  • To determine the antibiotic sensitivity profiles of S. aureus strains isolated from pediatric patients with intestinal dysbiosis.
  • To assess the susceptibility of MRSA and Methicillin-sensitive S. aureus (MSSA) strains to various antibiotics and bacteriophages.

Summary:

  • A significant proportion of S. aureus strains, including MRSA, exhibited polyresistance.
  • MRSA strains showed varying susceptibility to antibiotics, with high sensitivity to vancomycin and moderate sensitivity to others. MSSA strains were generally more sensitive.
  • Resistance to bacteriophages was noted in both MRSA and MSSA strains, with suppression of gut microflora identified as a risk factor.

Impact:

  • Highlights the challenge of treating staphylococcal infections in children with dysbiosis due to antibiotic resistance.
  • Informs clinical management strategies by identifying effective antibiotics against prevalent S. aureus strains.
  • Underscores the importance of maintaining gut microbiota balance to prevent gastrointestinal staphylococcal infections.

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