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Bioactive factors in human milk.

M Hamosh1

  • 1Department of Pediatrics, Georgetown University Medical Center, Washington, District of Columbia, USA. phamosh@excite.com

Pediatric Clinics of North America
|March 10, 2001
PubMed
Summary
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Human milk contains bioactive components that offer immune and non-immune protection. These nutrients, including cytokines and enzymes, support newborn health and digestion.

Area of Science:

  • Nutritional Science
  • Immunology
  • Pediatrics

Background:

  • Human milk is a complex biological fluid crucial for infant nutrition and development.
  • It contains a wide array of bioactive components beyond basic nutrients.
  • Understanding these components is key to appreciating human milk's protective functions.

Purpose of the Study:

  • To review the bioactive components of human milk.
  • To emphasize the immune and non-immune protective roles of human milk nutrients.
  • To discuss immune-modulating factors and digestive enzymes in milk.

Main Methods:

  • Literature review of scientific articles on human milk composition and function.
  • Analysis of studies focusing on bioactive components like cytokines, nucleotides, hormones, growth factors, and enzymes.

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  • Synthesis of information regarding the protective functions of these components.

    • Main Results:

    • Human milk contains major and minor nutrients with significant immune and non-immune protective functions.
    • Key immune-modulating components include cytokines, nucleotides, hormones, and growth factors.
    • Milk enzymes play a vital role in the digestive processes of newborns.

    Conclusions:

    • Bioactive components in human milk are essential for infant health, providing both immune defense and digestive support.
    • The comprehensive nutritional and immunological profile of human milk underscores its importance for infant well-being.
    • Further research into these components can inform infant feeding practices and health outcomes.