Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

What is the Endocrine System?00:46

What is the Endocrine System?

The endocrine system sends hormones—chemical signals—through the bloodstream to target cells—the cells the hormones selectively affect. These signals are produced in endocrine cells, secreted into the extracellular fluid, and then diffuse into the blood. Eventually, they diffuse out of the blood and bind to target cells which have specialized receptors to recognize the hormones.
Overview of Fatty Acid Metabolism01:28

Overview of Fatty Acid Metabolism

Lipids also are sources of energy that power cellular processes. Like carbohydrates, lipids are composed of carbon, hydrogen, and oxygen, but these atoms are arranged differently. Most lipids are nonpolar and hydrophobic. Major types include fats and oils, waxes, phospholipids, and steroids.
Fatty acids are catabolized in a process called beta-oxidation, which takes place in the matrix of the mitochondria and converts their fatty acid chains into two-carbon units of acetyl groups. The acetyl...
An Overview of the Endocrine System01:10

An Overview of the Endocrine System

The endocrine system, a complex network of glands, orchestrates physiological balance within the body through the production and secretion of hormones. These hormones are chemical messengers in intercellular communication, acting as conduits between the secretory cells and distant target sites. They traverse the circulatory system by being released into the extracellular fluid, and their impact is specific to cells possessing receptors for a particular hormone.
The endocrine system collaborates...
Structures of the Endocrine System00:59

Structures of the Endocrine System

The intricate framework of the endocrine system encompasses a diverse array of glands, with their target tissues and organs strategically distributed throughout the body. Central to this network are the endocrine glands, specialized structures that lack ducts and release hormones directly into the interstitial fluid. Notably, the hypothalamus, a vital neuroendocrine organ situated in the brain, governs neural functions and serves as a potent source of hormonal regulation. Near the hypothalamus...
Chemical Signaling in the Endocrine System01:08

Chemical Signaling in the Endocrine System

A signaling cascade is a series of events that facilitates the transmission of information within or between cells, culminating in a targeted response in the recipient cell. As chemical messengers, hormones are pivotal in initiating and modulating these intricate signaling cascades based on their solubility.
Lipid-soluble hormones, such as steroid hormones, demonstrate an intracellular action. These hormones traverse cell membranes due to their lipid nature. Once inside the target cell, they...
The Endocrine System01:29

The Endocrine System

The endocrine system is an extensive network of glands – organs or tissues in the body that create chemicals that control many bodily functions, that secrete hormones, which are chemical messengers that play essential roles in regulating various bodily functions. These hormones are secreted into the bloodstream and travel throughout the body. They require specific receptors to convey signals to cells possessing these corresponding receptors. This complex signaling mechanism ensures that every...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Opioid Peptides, Adrenocorticotrophic Hormone and Dietary Copper Intake in Humans.

Nutritional neuroscience·2016
Same author

Leptin and its relation to obesity and insulin in the SHR/N-corpulent rat, a model of type II diabetes mellitus.

International journal of experimental diabetes research·2002
Same author

Protective effects of dietary phytoestrogens in chronic renal disease.

Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation·2001
Same author

Dietary phytoestrogens: a possible role in renal disease protection.

American journal of kidney diseases : the official journal of the National Kidney Foundation·2001
Same author

Is adrenomedullin a causal agent in some cases of type 2 diabetes?

Peptides·2000
Same author

Role of angiotensin-converting enzyme inhibition in glucose metabolism and renal injury in diabetes.

Metabolism: clinical and experimental·1998

Related Experiment Video

Updated: Jul 20, 2026

Measuring Oral Fatty Acid Thresholds, Fat Perception, Fatty Food Liking, and Papillae Density in Humans
10:29

Measuring Oral Fatty Acid Thresholds, Fat Perception, Fatty Food Liking, and Papillae Density in Humans

Published on: June 4, 2014

Relationship between fatty acids and the endocrine system.

S J Bhathena1

  • 1Phytonutrients Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, USDA, MD 20705, USA. bhathena@307.bhnrc.usda.gov

Biofactors (Oxford, England)
|March 10, 2001
PubMed
Summary

Fatty acids and hormones significantly interact, influencing lipid metabolism and chronic diseases. Dietary fats, like polyunsaturated fatty acids (PUFA), impact insulin levels and resistance, affecting overall health.

More Related Videos

Saturated Fatty Acids Induce Ceramide-associated Macrophage Cell Death
08:26

Saturated Fatty Acids Induce Ceramide-associated Macrophage Cell Death

Published on: October 31, 2017

Quantification of Endothelial Fatty Acid Uptake using Fluorescent Fatty Acid Analogs
06:03

Quantification of Endothelial Fatty Acid Uptake using Fluorescent Fatty Acid Analogs

Published on: August 15, 2025

Related Experiment Videos

Last Updated: Jul 20, 2026

Measuring Oral Fatty Acid Thresholds, Fat Perception, Fatty Food Liking, and Papillae Density in Humans
10:29

Measuring Oral Fatty Acid Thresholds, Fat Perception, Fatty Food Liking, and Papillae Density in Humans

Published on: June 4, 2014

Saturated Fatty Acids Induce Ceramide-associated Macrophage Cell Death
08:26

Saturated Fatty Acids Induce Ceramide-associated Macrophage Cell Death

Published on: October 31, 2017

Quantification of Endothelial Fatty Acid Uptake using Fluorescent Fatty Acid Analogs
06:03

Quantification of Endothelial Fatty Acid Uptake using Fluorescent Fatty Acid Analogs

Published on: August 15, 2025

Area of Science:

  • Endocrinology
  • Nutritional Science
  • Biochemistry

Background:

  • The endocrine system and fatty acids exhibit complex bidirectional interactions.
  • Hormones regulate fatty acid metabolism and tissue lipid composition.
  • Chronic diseases like diabetes and cardiovascular disease involve altered hormone levels and lipid profiles.

Purpose of the Study:

  • To elucidate the intricate relationship between fatty acids and the endocrine system.
  • To understand how hormones influence fatty acid metabolism and vice versa.
  • To explore the role of specific fatty acids in hormonal regulation and disease states.

Main Methods:

  • Review of hormonal regulation of lipogenesis and lipolysis.
  • Analysis of hormone-fatty acid interactions in chronic degenerative conditions.
  • Investigation of neuropeptide involvement in lipid metabolism.
  • Examination of polyunsaturated fatty acids (PUFA) as precursors for hormone-like eicosanoids.

Main Results:

  • Hormones like insulin, glucagon, and cortisol critically control fatty acid metabolism.
  • Saturated and trans fatty acids (TFA) are linked to decreased insulin concentration and insulin resistance.
  • Polyunsaturated fatty acids (PUFA) are associated with increased plasma insulin concentration and reduced insulin resistance.
  • Omega-3 PUFA in humans have been shown to modulate opioid peptide levels.

Conclusions:

  • Fatty acids significantly influence endocrine function, affecting hormone and neuropeptide levels and receptor activity.
  • Dietary fatty acid composition plays a crucial role in metabolic health and the development of chronic diseases.
  • Understanding these interactions is vital for developing targeted nutritional and therapeutic strategies for endocrine and metabolic disorders.