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In vivo Liver Endocytosis Followed by Purification of Liver Cells by Liver Perfusion
Published on: November 10, 2011
The interaction of tributyllead with lysosomes from rat liver
M Bragadin1, D Marton, S Manente
1Dipartimento Scienze Ambientali, Università di Venezia, Italy. bragadin@unive.it
Journal of Inorganic Biochemistry
|March 10, 2001
Abstract:
The interactions of tributyllead with lysosomes from rat liver have been studied. It results that the organometal compound induces a fast alkalinization in energized lysosomes. The interpretation is that the compound is a potent proton carrier. This function could explain the toxicity, in particular at neurological level of the compound.
