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Energy expenditure in infants with pulmonary insufficiency: is there evidence for increased energy needs?

S C Denne1

  • 1Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202, USA. sdenne@iupui.eduñ

The Journal of Nutrition
|March 10, 2001
PubMed

Insights

Infants with pulmonary insufficiency may experience growth failure due to high energy expenditure. The doubly labeled water technique confirms increased energy needs in infants with chronic lung disease and other critical conditions.

Area of Science:

  • Pediatric Medicine
  • Neonatology
  • Physiology

Background:

  • Growth failure in infants is often linked to high energy expenditure.
  • Indirect calorimetry has provided inconsistent results for assessing infant energy expenditure.
  • Newer techniques are needed to accurately measure energy expenditure in infants.

Purpose of the Study:

  • To evaluate the utility of the doubly labeled water technique in assessing energy expenditure in infants.
  • To investigate the relationship between pulmonary insufficiency and energy expenditure in infants.

Main Methods:

  • Utilized the doubly labeled water technique to measure energy expenditure.
  • Compared energy expenditure in infants with various clinical conditions, including pulmonary insufficiency, chronic lung disease, and congenital heart disease.
  • Included extremely low birth weight infants and minimally ill infants.

Main Results:

  • The doubly labeled water technique provided evidence for increased energy expenditure in infants with chronic lung disease and congenital heart disease.
  • Elevated energy expenditure was also observed in minimally ill, extremely low birth weight infants.
  • This technique shows promise for studying energy expenditure in diverse infant populations.

Conclusions:

  • The doubly labeled water technique is a valuable tool for accurately assessing energy expenditure in infants.
  • Increased energy expenditure is a significant factor contributing to growth failure in infants with pulmonary insufficiency and other critical conditions.
  • Further research using this method can elucidate energy metabolism in various pediatric clinical settings.

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