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A freeze-fracture study of the junctions between glomerular epithelial cells in aminonucleoside nephrosis
Abstract:
In rats with aminonucleoside nephrosis, glomerular slit pores are mostly replaced by sites of close apposition between adjacent epithelial cell membranes. In replicas of freeze-fractured glomeruli, such junctions showed incomplete fibrils or grooves typical of "leaky" zonulae occludentes.