Related Experiment Video

Updated: Jul 8, 2026

Analysis of SNARE-mediated Membrane Fusion Using an Enzymatic Cell Fusion Assay
09:19

Analysis of SNARE-mediated Membrane Fusion Using an Enzymatic Cell Fusion Assay

Published on: October 19, 2012

SNARE complex oligomerization by synaphin/complexin is essential for synaptic vesicle exocytosis

H Tokumaru1, K Umayahara, L L Pellegrini

  • 1Department of Neurobiology, Duke University Medical Center, Box 3209, Durham, NC 27710, USA.

Cell
|March 10, 2001
PubMed
Summary

Synaphin/complexin protein promotes SNARE complex oligomerization, forming a scaffold essential for synaptic vesicle fusion and neurotransmitter release. Inhibiting this process blocks vesicle exocytosis.

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